HistoAtlas

HistoAtlas provides a comprehensive web atlas for exploring cancer tissue morphology in relation to molecular programs and patient survival across 21 cancer types. Key features include: * Analysis of 6,745 H&E-stained diagnostic slides from TCGA * Extraction of 38 quantitative histomic features * Precomputed statistical associations linking tissue architecture to genes, pathways, mutations, immune subtypes, and clinical outcomes * Coverage of tumor morphology, immune infiltration, spatial organization, and cell densities This platform allows researchers to delve into over 10,000 statistical associations, offering profound insights into how tissue architecture correlates with various biological markers and clinical trajectories. It serves as a vital resource for understanding the complex interplay between microscopic tissue characteristics and macroscopic patient outcomes. HistoAtlas is entirely free and requires no login, making it easily accessible for a broad range of users. It is an invaluable tool for oncology researchers, pathologists, and bioinformaticians seeking to integrate morphological data with molecular and clinical information to advance cancer research and diagnostics.